A study of 1300 men with average age 62 revealed that those with excessive anger are 3 times more likely to develop heart disease than the rest. Another research done at Johns Hopkins School of Medicine tracked 1,055 medical students for 36 years. The hotheads were found to be 6 times more likely to suffer heart attacks by age 55 than the cooler heads and 3 times more likely to develop any form of heart or blood vessel disease.

One study, published in 1995, found that, during two hours after an angry outburst, a individual’s risk of having a heart attack was more than twice that of someone who had not lost their cool. Out of 1,623 people in that study, 501 were women.

The above studies clearly demonstrate a correlation between excessive ire and susceptibility to heart disease.